A brief list of examples has been created to inform you of the alternative methods of testing that does not involve the use on animals.
1. For example, to test for skin corrosivity and irritation that a product may cause, it can easily be measured using 3 dimensional human skin equivalent systems such as SkinEthic (a model of constructed human epithelium.)and other brand EpiDerm. Other alternatives is the use of sophistic, computer based Quantitative Structure Activity Relationship (QSAR) models that predict skin corrosivity and irritation by ,means of correlating a new drug or chemical with its likely activity properties, and effects with an accuracy rate of 90-95 percent. 1. Tissue Models. (n.d.). Retrieved October 15, 2016, from http://www.mattek.com/products/epiderm
2.To test skin hydration the electrical impedance of EpiDerm is measured to assess the efficacy of topically applied moisturizers including creams, gels and lotions. The Skin Hydration protocol allows for data analysis within 24 hours. 2. Applications. (n.d.). Retrieved October 15, 2016, from http://www.mattek.com/products/epiderm/
3. Identify phototoxic effects of topical or systemic test substances using the EpiDerm Phototoxicity Assay . 3. Applications. (n.d.). Retrieved October 15, 2016, from http://www.episkin.com/pageLibre000100c5.asp
